Fig. 2

Figure 2. Characterization of intestine phenotype after 6 weeks of HCC induction through Alcian blue-periodic acid-Schiff (AB-PAS) stain. (A) Representative images of AB-PAS staining in all three intestine segments. Scale bar in red 50 μm. (B–E) Quantification of eosinophil counts (B), goblet cell counts (C), goblet cell size (D) and bowel wall thickness (E) in wt vs. xmrk intestine. Bowel wall was measured from the trough between two villi to the outer edge of the intestine (shown as a yellow line in the top left representative image). Black arrowheads indicate fuchsia-colored eosinophils, and white arrowheads indicate bluish-purple goblet cells. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.