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Figure 4 Network analysis of AD and PD gene co-expression modules. (A) Gene co-expression networks were constructed from transcriptomic data from AD and PD samples. Community analysis was used to identify gene modules (see the Materials and Methods section). Modules with at least 30 genes are shown as nodes. Node size indicates number of genes. Nodes are coloured by network of origin and numbered in descending order of module size. Shared genes between modules are shown as edges. Edge weight indicates number of shared genes. (B) Degree distribution of AD, PD, and random networks. (C) Enrichment analysis was performed on gene modules containing at least 30 genes using the KEGG database (see the Materials and Methods section). Significantly enriched gene modules are shown as coloured, numbered blocks. Colour and number keys are as in (A).