ZFIN Image: Allen et al., 2021, Figure 3

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Figure Caption

Figure 3

Extravasated circulating tumor cells downregulate extracellular matrix remodeling. (A) Gene regulatory networks for the extracellular matrix remodeling pathway in HMPOS and (B). D17. Blue denotes downregulation and red denotes upregulation (FDR < 0.05). Nodes are scaled proportionally to log2FC, with larger nodes depicting greater log2FC between extravasated and parental cell lines. (C) Scatter plot of sum rank of network connectivity parameters by log2FC for HMPOS and (D) D17. (E) Bar graphs of top connected genes in the pathway, colored by log2FC for HMPOS and (F) D17.

Acknowledgments

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