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Figure 8
Overview of the differentially expressed genes in response to DINCH. The schematic diagram shows the regulation and involvement of genes in different signaling mechanisms. Gene involved in lipid synthesis, elongation, hydrolysis and transport were altered in larvae. The stress response and DNA repair genes were also regulated following DINCH exposure. The altered lipid metabolism and transport could also be responsible for the observed cholesterol biosynthesis/homeostasis and brain function alteration in the larvae. The upregulated genes are indicated in red color, the downregulated genes are indicated in green color and the genes that were not regulated are indicated in black color.