ZFIN Image: Gourain et al., 2021, FIGURE 3

Image

Figure Caption

FIGURE 3

Alteration in cholesterol metabolism in response to brain injury. (A) Increases in level of transcripts coding for cholesterol synthesizing enzymes (green) and decreased level of transcripts coding for transporter involved in ferrying cholesterol through the body and across membrane (red) were identified. Products and substrates are represented in blue boxes and enzymatic reactions by blue arrows. The double black arrow represents flow across membrane. (B,C) Changes in levels of mRNA were validated comparing the quantification by qRT-PCR of mRNAs encoding three selected enzymes synthesizing cholesterol (B) and two transporters (C) in three independent control (yellow) and injured (blue) telencephalic hemispheres (n = 3). *p-value = 0.05, **p-value < 10^{– 03}.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Neurosci.