ZFIN Image: Liedtke et al., 2020, Figure 4

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Figure Caption

Figure 4

TNAP function is linked to PLP/cofactor, neurotrophic factor and myelin synthesis. (A) TNAP’s influence on the GABA synthesis. (B) TNAP’s role in the catecholamine and serotonin synthesis. (C) TNAP’s impact on purinergic signaling. (D) TNAP’s role in the myelin synthesis pathway. HTP: 5-hydroxytryptophan, AADC: aromatic L-amino acid decarboxylase, ATP/ADP/AMP: adenosine tri-/di-/monophosphate, BBB: blood–brain barrier, GABA: gamma-aminobutyric acid, GAD: glutamate decarboxylase, L-DOPA: levodopa, PDXK: pyridoxal kinase, PLP: pyridoxal-5′-phosphate, TNAP: tissue-nonspecific alkaline phosphatase.

Acknowledgments

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