ZFIN Image: Takamiya et al., 2020, Fig 10

Image

Figure Caption

Fig 10 TGFβ signalling in the lens is required for corneal endothelium formation.

(A-N) Tg(smad3:GFP) embryos were examined from 22–96 hpf for in situ expression of tgfb2 (A-G) and gfp (H-N). The dotted line outlines the lens. Arrows and arrowheads indicate expression in the lens and mesenchymal cells, respectively. (O-P) Tg(corneaEndo:GFP) embryos were treated with either 1% DMSO (O) or TGFβ inhibitor (30 μM SB-505124; P) from 28 to72 hpf (stages 3–4). Orientations: dorsal (D), ventral (V), nasal (N) and temporal (T). Ln: lens. The dotted lines outline lens and eye cup. Scale bars: 50 μm.

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