ZFIN Image: Wang et al., 2019, Fig. 4.

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Figure Caption

Fig. 4.

Heat pre-conditioning suppresses stress granule formation. (A) Representative images showing stress granule formation in midbrain and retina cells of 1 dpf GFP–G3BP1 knock-in zebrafish with indicated treatment paradigms. Control, fish kept at ambient temperature 28°C; 35°C 6 h, fish kept at 35°C for 6 h; 42°C 10 min, fish heat-shocked at 42°C for 10 min; 35°C for 6 h+42°C 10 min, fish first exposed to 35°C for 6 h, then heat-shocked for 10 min at 42°C. Scale bar: 10 µm. (B) Mean±s.e.m. percentage of zebrafish with stress granules detected in the midbrain. Data from two independent experiments, with n=10, 7, 19 and 17 fish for each condition. **P≤0.01 by unpaired Student's t-test.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.