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Fig. 6

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ZDB-IMAGE-190617-4
Source
Figures for Bose et al., 2018
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Fig. 6 A: 5 superimposed locomotor path traces of 48-h postfertilization (hpf) het/hom mutants without and with chronic application of BAY K 8644 (2 μM). B–D: swim duration (B), swim distance (C), and maximum velocity (D) were measured at 48 hpf in WT and het/hom mutants after chronic application of BAY K 8644 (2 μM) in the touch-evoked escape response (TEER) assay. het/hom mutants with treatment displayed significant recovery from locomotor defect in swim duration and swim distance of the TEER assay compared with het/hom mutants without treatment (paired t-test; P < 0.01). E: recordings of miniature end-plate currents (mEPCs) from 2-day postfertilization (dpf) het/hom mutants after chronic application of BAY K 8644 (2 μM). het/hom mutants showed a significant recovery in mEPC frequency (paired t-test; **P < 0.01). F and G: distance swam (F) and mean velocity (G) at 5 dpf by het/hom mutants untreated and treated with BAY K 8644 (2 μM) for 4 days. **P < 0.01.

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