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Fig. 2
Epicardial regeneration. (A) Schematic for epicardial ablation and regeneration. The epicardium is shown in green color. The white arrows indicate the directions of epicardial cell migration; (B) explanted adult zebrafish hearts were imaged daily post epicardial ablation. The epicardial cell sheet regenerates along the ventricular surface in a base-to-apex direction (arrows). The nuclei of epicardial cells are labeled with nuclear GFP (tcf21:nucEGFP). White dashed lines outline the ventricles, and red dashed lines indicate the leading edge of the migrating epicardial cell sheet. Scale bar: 200 μm. BA, bulbous arteriosus; v, ventricle; dpi, days post injury.