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Fig. 4
Stabilizing of β-catenin by gsk3β inhibition partially restores the head size deficit.
a Western blot analysis of β-catenin. b Lateral views of representative larvae (3 dpf) exposed to DMSO, PMA or PMA+LiCl. Head size was calculated with the boundary shown in yellow dotted line. c Quantitative representation of body length and head size (3 dpf) normalized to DMSO (DMSO n = 14, PMA n = 18, PMA+LiCl 50 mM n = 12, PMA+LiCl 100 mM n = 18, *p < 0.05, ***p < 0.001, one-way ANOVA)
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