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Fig. S6
Vascular specific overexpression of Etv2 does not result in expansion of lymphatic progenitors.
Injection of fli1a:etv2-2a-mCherry (B-B’’) does not result in expansion of prox1a:GFP+ cells (arrowheads) etv2 at 30hpf (5.6±0.5, n=5) compared to control injection of kdrl:mCherry (A-A’) (6.3±0.6, n=7). Quantification of number of prox1a+ cells in the vasculature (C) (two-tailed Student’s t test p= 0.41). Mean±SEM is shown. Experiment has been repeated twice.
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Reprinted from Developmental Biology, 440(1), Davis, J.A., Koenig, A.L., Lubert, A., Chestnut, B., Liu, F., Desai, S.P., Winkler, T., Pociute, K., Choi, K., Sumanas, S., ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression, 40-52, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.