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Fig. 1
Screening for inhibitors of melanogenesis from Crataegus pycnoloba extracts. Crude extract (A) and fractions (C–J) were tested for anti-pigmentation ability by in vivo zebrafish assay. Synchronized 24 hpf embryos were treated with 0.04 mg/mL of the crude extract and 0.1 mg/mL (CPC-Fr6-8) or 0.01 mg/mL (CPC-Fr9-13) from the different fractions for 24 h. Images were obtained at 48 hpf using a stereomicroscope. Test compounds were dissolved in DMSO. (B) Control treated embryo. Scale bar: 100 μM.
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