ZFIN Image: Sedykh et al., 2017, Fig. 2

Image

Figure Caption

Fig. 2

Aberrant curvature in rfx4 mutant and morphant embryos. Heterozygous rfx4^uw8013 embryos develop normally (A), while their homozygous siblings show pronounced downward curvature (B) by 2 dpf. C: PCR genotyping of individual progeny of rfx4^uw8013/ + parents shows that the curved phenotype is linked to rfx4^uw8013 homozygosity. D,E: Embryos injected with translation‐blocking morpholino targeting rfx4 develop with downward curvature. F: The aberrant curved morphology in rfx4 morphants is independent of apoptosis. Summarized from four experiments. e, embryos.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.