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Fig. S3
Defect of HSPC emergence is specifically caused by miR-142a-3p but not miR-142a-5p.
(a) 142C-/- embryos showed decreased expression of HSPC marker runx1 at 26 and 36 hpf and cmyb at 36 hpf by WISH. (b) HSPC differentiated lineages showed reduction in 142C-/- embryos including erythrocytes (gata1), neutrophils (lyz) and lymphocytes (rag1) at 4 dpf by WISH. (c) MiR-142a-5p MO injected embryos displayed normal expression of HSC marker runx1 by WISH at 36 hpf.
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