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Fig. S7
Blockade of inhibitory inputs facilitates the occurrence of BC waves.
(a) Pseudocolor time-lapse images showing BC calcium activities before (top) and 20 min after bath application of picrotoxin (PTX, 200 μM) in a 3-dpf Tg(Gal4-VP16xfz43,UAS:GCaMP1.6) larva, which only exhibited local spontaneous calcium activities under control condition.
(b) Summary of data obtained from 9 larvae.
(c) Superposition of the initiation site of 76 BC calcium waves occurred under bath application of PTX. ***P < 0.001; two-tailed paired Student’s t-test. Data are represented as mean ± s.e.m.
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