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Fig. 5

ID
ZDB-IMAGE-170606-13
Source
Figures for Modrell et al., 2017
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Figure Caption

Fig. 5

Two beta-parvalbumin genes are differentially expressed in ampullary organs versus neuromasts.

(A) Phylogenetic analysis of selected vertebrate parvalbumin proteins shows three clades: the alpha-parvalbumins, plus two clades containing beta-parvalbumins: the first includes the mammalian beta-parvalbumins, i.e., oncomodulins, and chicken Pvalb3/thymic CPV3. One of the paddlefish lateral line-enriched parvalbumin genes encodes a protein that groups within the beta-parvalbumin clade containing the oncomodulins, so we have named it Pvalbβ1/Ocm. The other falls within the second beta-parvalbumin clade, so we have named it Pvalbβ2. (B) In situ hybridization shows that Pvalbβ1/Ocm is expressed in both ampullary organs and neuromasts, while (C) Pvalbβ2 is restricted to ampullary organs. Scale bars: 100 µm and 20 µm.

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