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Fig. 6
The anterior migration of cranial neural crest initiates the morphological division of peripheral and central olfactory system. Stills from movie using sox10:RFP;Bactin:Gap43-GFP embryos. A,B: Starting at 14 somite stage (ss), cells that will form olfactory placode (OP) (green, arrowheads) lose their rounded appearance. CNC cells (red) advance anteriorly moving between the compacting OP and the neural tube. C,D: As the CNC cells move anteriorly the cells change shape (red, asterisk) appearing to squeeze between the forming the neural tube and OP. Movies were initiated at 14 ss and ended 3 hr later at 19–20 ss (n = 6). Dorsal view; anterior toward bottom of page. GFP, green fluorescent protein; RFP, red fluorescent protein. Scale bar = 25 µm (see Supp. Movie S7).