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Fig. 5 S1
PDGF signaling is required after gastrulation for proper cardiac fusion.
(A,B) Dorsal views, anterior to the top, display myl7 expression at 22 s in representative embryos treated with DMSO (A) or Pdgfr inhibitor V (B) from the tailbud stage until 22 s. DMSO-treated control embryos exhibited normal cardiac fusion, whereas treatment with Pdgfr inhibitor V disrupted cardiac fusion. See Figure 2—figure supplement 2 for additional information on the prevalence of these phenotypes. Scale bar: 60 μm.
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