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Fig. 7
OPCs migrate dorsally normally despite reduction in reticulospinal axons.
A, B, Time-lapse stills of Tg(olig2:EGFP; sox10:mRFP), WT (A) or kbp mutant (B) larvae, showing two OPCs (arrowheads) migrating dorsally above the olig2:EGFP band of motor neurons and pMN precursors (dashed line). Scale bar: 10μm. C, The rate at which OPCs accumulate in the dorsal spinal cord is similar between WTs and mutants in 425μm long regions. Data from N = 18 WT and N = 13 mutants (anterior) and N = 17 WT and N = 19 mutants (posterior). Error bars indicate ± SD.
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