ZFIN Image: Nakayama et al., 2013, Fig. S8

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Figure Caption

Fig. S8

Effects of gbx2-ΔNCR overexpression on FGF signaling in embryos. Embryos were injected with mRNA for egfp and gbx2-ΔNCR (100 pg/embryo) and examined at the bud stage (left two columns) or at 26 hpf (right two columns) for the expression of the FGF downstream genes specified on the left. The most striking phenotypes and their proportions are shown in the respective panels. (a–h) Dorsal views with anterior to the top (a, b, e, f) or to the left (c, d, g, h). (a′–h′) Lateral views with anterior to the top and dorsal to the right (a′, b′, e′, f′) or with anterior to the left and dorsal to the top (c′, d′, g′, h′). Normal and disrupted MHB/isthmuses are marked with solid and open triangles, respectively. Scale bars, 200 µm.

Acknowledgments

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Reprinted from Mechanisms of Development, 130(11-12), Nakayama, Y., Kikuta, H., Kanai, M., Yoshikawa, K., Kawamura, A., Kobayashi, K., Wang, Z., Khan, A., Kawakami, K., and Yamasu, K., Gbx2 functions as a transcriptional repressor to regulate the specification and morphogenesis of the mid-hindbrain junction in a dosage- and stage-dependent manner, 532-52, Copyright (2013) with permission from Elsevier. Full text @ Mech. Dev.