ZFIN ID: ZDB-IMAGE-140530-21
USH2 proteins accumulate in the ER in ush1c mutants. (A-D) Wild-type siblings. (E,F) ush1c mutants. (A,E) KDEL, a marker of the ER, is expanded in ush1c mutants. (B-D,F-H) USH2 proteins are stuck at the level of the ER in ush1c mutants. (B,F) Colocalization of Ush2a and KDEL. (C,G) Colocalization of Gpr98 and KDEL. (D,H) Colocalization Whirlinb and KDEL. USH2 proteins can be detected at low levels in the region of the ER (B-D). Colocalization signal between USH2 proteins and KDEL is remarkably increased in ush1c mutants. Some cell bodies are outlined. Scale bar: 5µm
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