ZFIN Image: Uribe et al., 2013, Fig. 5

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Figure Caption

Fig. 5 Gentamicin treatment increases the numbers of TUNEL-labeled cells in the adult utricle.

Adult wildtype zebrafish received either a single intraperitoneal injection of (A) buffer or (B) 250 mg/kg gentamicin and allowed to recover for either 4 or 24 hours (4 hour data is shown). Fixed utricles were processed using a TUNEL-kit to label apoptotic cells (green cells) and co-labeled with DAPI (blue cells). (A–B) Low power (10X) images of the utricle reveals few TUNEL-labeled cells scattered throughout the utricle of a (A) buffer-treated animal but more cells with TUNEL-labeling in the (B) gentamicin-treated animal. (C) Mean number of TUNEL-labeled cells (± SD) in the utricles of buffer- or gentamicin-injected zebrafish. *p<0.05 or ***p<0.001; n = 9–12; M = medial, R = rostral.

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Acknowledgments

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