ZFIN Image: Littleton et al., 2012, Fig. 3

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Figure Caption

Fig. 3 Cardiac Output (CO) Decreases with Increasing Cholesterol (CH) Dose. A. Measurement of ventricular diastole and systole in TG(Kdrl:mCherry)/Casper transgenic to derive stroke volume (SV) in order to finally calculate CO B. CO decreases with increasing CH dose from 0.1-8%HCD (R = 0.397, R² = 0.158). Difference between 0.1% and 8%HCD effect on CO is significant C. SV also decreases with increasing CH dose from 0.1-8%HCD (R = 0.396, R² = 0.157). Difference between 0.1% and 8%HCD effect on SV is significant C. There is not a relationship between HR and CH dose. * P < 0.05, points are mean ± S.D. 1-way ANOVA, Holm-Sidak post-hoc analysis. n = 12-13 per group.

Acknowledgments

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