ZFIN Image: Grandel et al., 2011, Fig. 1

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Figure Caption

Fig. 1

Phenotypic analysis of nls^u11 mutant and sibling embryos and larvae. A–H: Scanning electron micrographs (A,B) and stereomicroscopic images (C–H). Dorsal views, anterior is to the left. A: At 3 days postfertilization (dpf), wild-type siblings show pectoral fins apposed to the yolk. B: No pectoral fins are seen in most nls^u11 mutants (arrows in A and B). C:tbx5 expression marks the initially contiguous heart (arrowhead) and pectoral fin (asterisk) primordia in wild-types at the 10s stage. E: The fin precursor specific tbx5 expression domain lateral to somites 1–3 (asterisk) has separated from the heart field domain (arrowhead). G: Pectoral fin buds retain tbx5 expression at 32 hr (asterisk). D,F: A fin precursor specific tbx5 expression domain is lacking at all stages in nls^u11 embryos (asterisks). H: This prefigures the later observed lack of pectoral fin buds (asterisk).

Acknowledgments

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