ZFIN Image: Lam et al., 2011, Fig. 2

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Figure Caption

Fig. 2

Phenotype analysis of BPA early-life exposure toxicity in GFP transgenic fish larvae.

(A) Tg(Nkx2.2a-mEGFP) zebrafish larvae exposed to vehicle (control), 500 μg/L BPA and 5000 μg/L BPA. Panel on the right represent the inset region marked by white-outlined box in the corresponding left panel. White arrows indicate axon branching which are normal in control fish but marginally and severely affected in fish exposed to 500 and 5000 μg/L BPA, respectively. (B) ET(krt8-EGFP)^sqet20 zebrafish larvae exposed to vehicle (control), 500 μg/L BPA and 5000 μg/L BPA. Panel on the right represent the inset region marked by white-outlined box in the corresponding left panel. White arrows indicate neuromast cells which are rosette circular-like shape in control fish but severely deformed in fish exposed to 500 and 5000 μg/L BPA. (C) Tg(Flia-EGFP)^y1 zebrafish larvae exposed to vehicle (control), 500 μg/L and 5000 μg/L BPA. White arrow indicate vascularization in abdominal region which is normal in control fish but suppressed in fish exposed to 500 and (R) 5000 μg/L BPA.

Acknowledgments

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