ZFIN Image: England et al., 2011, Fig. 13

Image

Figure Caption

Fig. 13 DEAB treatment causes a reduction in cell proliferation. (A-D) Lateral views of phospho-Histone H3 staining in DMSO-treated control and DEAB-treated spinal cords of WT zebrafish embryos and smo mutants at 24 hpf. Scale bar: 50 μm. (E) Average number (n=5 embryos) of phospho-Histone H3-positive cells in spinal cord adjacent to somites 6-10. Statistically significant differences between embryos of the same genotype are indicated (^*, P<0.05, Student’s t-test). Error bars denote s.d. (F,G) dorsal views of hindbrain showing dramatically reduced egr2b expression in rhombomere (r) 5 and the loss of hoxb4a expression in the anterior spinal cord of DEAB-treated embryos (G).

Acknowledgments

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