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Fig. 3
Cxcl12 subfunctionalization affects the function of the Cxcl12 paralogs in gastrulation. (A) Knockdown of Cxcl12b slows down the migration of endodermal cells. Note the gap between the forerunner (arrowheads) and the endodermal cells. (B) The gastrulation phenotype induced by knockdown of Cxcl12b is effectively reverted by wild-type Cxcl12b as well as by the N33S Cxcl12a protein. Error bars depict s.e.m.
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