ZFIN Image: Harrison et al., 2011, Fig. 1

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Figure Caption

Fig. 1 Hdac1 inhibits Histone acetylation and promotes H3K9 methylation levels in the zebrafish embryo. Levels of Hdac1 protein and covalently modified histones in hdac1 mutant (m) and wild-type (s) embryos aged 27, 33, 39, 48, 56, 73, 80 and 96 hpf, visualised by Western blot analysis using anti-Hdac1 and histone modification-specific antibodies. Hdac1 protein visualised with an anti-Hdac1 antibody is shown on the top row. Antibodies specific for the following histone modifications were: Pan-acetyl lysine; acetyl-H3K9; dimethyl-H3K9, trimethyl-H3K4. An anti-H3 antibody was used as a loading control (bottom row).

Acknowledgments

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