IMAGE

Fig. S4

ID
ZDB-IMAGE-091113-108
Source
Figures for Sanek et al., 2009
Image
Figure Caption

Fig. S4 pax2a patterning defects are detected prior to fgf patterning defects in zic2a morphants. fgf8a expression is normal at 16s in control (A, 11/11 embryos) and zic2a morphants (B, 8/8 embryos). Similarly, spry4 is unaffected at 16s in control (C, 21/21 embryos, n=2) or zic2a morphants (D, 22/24 embryos, n=2). pax2a is expressed broadly in the OS and retinal primoridia at 16s (E, 15/15 embryos, n=2), and might be slightly expanded in zic2a morphants (F, 9/21 embryos, n=2). At 19s, fgf8a is weakly expressed in the presumptive OS (G, 12/12 embryos), and its expression is unaffected by knocking-down Zic2a (H, 9/9 embryos). spry4 is expressed in a broader domain than fgf8a (I, 20/20 embryos, n=2), and also appears unaffected in zic2a morphants (J, 21/25 embryos, n=2). pax2a expression has begun retracting from the retinal primordium by 19s in control embryos (K, 8/18, n=2), but not in zic2aMO-injected embryos (L, 9/15 embryos, n=2). Arrowheads mark the OS. All embryos are shown in ventral view, anterior to the left. Embryos in A-F are at 16s, while embryos in G-L are at 19s.

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