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Fig. S8
NO signaling affects vascular and HSC development.
(A) qPCR for ephrinB2 in WT and sih-/- in the presence and absence of SNAP. * sig vs. control, p<0.05, ANOVA, n=5.
(B-E) Effect of bradykinin (10 μM) on runx1/cmyb expression in wild-type and sih-/- embryos at 36 hpf. runx1/cmyb positive cells are highlighted by arrowheads.
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Reprinted from Cell, 137(4), North, T.E., Goessling, W., Peeters, M., Li, P., Ceol, C., Lord, A.M., Weber, G.J., Harris, J., Cutting, C.C., Huang, P., Dzierzak, E., and Zon, L.I., Hematopoietic stem cell development is dependent on blood flow, 736-748, Copyright (2009) with permission from Elsevier. Full text @ Cell