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Fig. 3 Embryonic abnormalities caused by dsRNA injection. (A) An embryo injected with pouII-1 sense RNA at the 50% epiboly stage. (B) An abnormal embryo injected with pouII-1 dsRNA at the same stage as in A. (C) An embryo injected with GFP sense RNA at the 75% epiboly stage. (D) An abnormal embryo injected with GFP dsRNA at the same stage as in C. (E) A 20-h embryo injected with pouII-1 sense RNA. (F) A 20-h abnormal embryo injected with pouII-1 dsRNA. (G) A 20-h abnormal embryo injected with GFP dsRNA. (H) Severely abnormal embryos at 20 hpf injected with intronT dsRNA.
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Reprinted from Developmental Biology, 229(1), Zhao, Z.X., Cao, Y., Li, M., and Meng, A.M., Double-stranded RNA injection produces nonspecific defects in zebrafish, 215-223, Copyright (2001) with permission from Elsevier. Full text @ Dev. Biol.