ZFIN Image: Hill et al., 2009, Fig. 3

Image

Figure Caption

Fig. 3 Early brain development appears normal in arnt2^-/- embryos at 24–48 hpf. Brain development in the arnt2^-/- mutant embryo was assessed by gross examination of the brain at the light microscopic level at 24 hpf. A dorsal view of the developing brain of a WT embryo and an arnt2^-/- embryo (A, B) and a lateral view of the brain of a WT embryo and an arnt2^-/- embryo (C, D) are shown. At 48 hpf a dorsal view of the brain of a representative WT embryo and arnt2^-/- embryo (E, F) is shown. White arrowheads point to ventricles in the brain of the WT and arnt2^-/- mutant, demonstrating that brain ventricles are similar in size and shape in the two genotypes (E, F). Overall, gross brain morphology of arnt2^-/- larvae at 24–48 hpf was indistinguishable from WT. Patterns of staining at 24 hpf are shown for whole-mount ISH of krox20 in a representative WT embryo and arnt2^-/- embryo at 24 hpf (G, H, arrowheads) and of pax6a (I, J, arrowheads).

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Zebrafish