Image
|
Figure Caption
Fig. 5 ptc expression in flh homozygotes. Transcripts were revealed by in situ hybridisation with antisense RNA probes to shh (A), ptc2 (B), and ptc1 (C). All panels show lateral views of the trunk of flh homozygotes above the yolk extension, at 24 hpf with anterior to the left. Expression of both ptc genes is lost from the somites and from most of the caudal trunk apart from around the groups of floor plate-like cells that still express shh and twhh. In addition, ptc2 expression extends more dorsally in the neural tube from these groups of cells than ptc1 expression does.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 208, Lewis, K.E., Concordet, J.P., and Ingham, P.W., Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to hedgehog signalling, 14-29, Copyright (1999) with permission from Elsevier. Full text @ Dev. Biol.