Epiphysial neurons which normally express islet-1 retain expression of islet-1 following transplantation to ectopic sites. (A) Lateral view of the embryo showing the TRITC–dextran-labeled donor cells in the host tectum. Arrowheads mark donor cells that expressed islet-1 mRNA that can be seen in B. (B) Same view as in A showing that some of the donor cells express islet-1 as determined by in situ hybridization to an islet-1 riboprobe. These cells are designated by arrowheads in A. Anterior is to the left and dorsal is up; scale, 25 μm.
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