Gene

sema3ab

ID
ZDB-GENE-991209-6
Name
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
Symbol
sema3ab Nomenclature History
Previous Names
  • sema3a2 (1)
  • semaZ1b
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Involved in branching involved in blood vessel morphogenesis; branching morphogenesis of a nerve; and motor neuron axon guidance. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in brain; myotome; pharyngeal arch; and somite. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 16 with or without anosmia. Orthologous to human SEMA3A (semaphorin 3A).
Genome Resources
Note
None
Expression
All Expression Data
8 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sema3ab Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 16 with or without anosmia Alliance {Hypogonadotropic hypogonadism 16 with or without anosmia} 614897
Associated With sema3ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001627 Sema domain
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR016201 PSI domain
Family IPR027231 Semaphorin
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Homologous_superfamily IPR036352 Sema domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype PSI domain Sema domain Sema domain superfamily Semaphorin WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A4JYE3 765
UniProtKB:A0A2R8QJX7 678
UniProtKB:Q9W686 778
UniProtKB:B3DIV3 778
UniProtKB:Q1LXC4 778
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations