Gene

ctnna1

ID
ZDB-GENE-991207-24
Name
catenin (cadherin-associated protein), alpha 1
Symbol
ctnna1 Nomenclature History
Previous Names
  • ctnna
  • dan[a]E
  • [a]E-catenin (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Exhibits actin filament binding activity and cadherin binding activity. Involved in tissue homeostasis. Localizes to several cellular components, including adherens junction; catenin complex; and microvillus. Human ortholog(s) of this gene implicated in patterned macular dystrophy 2. Orthologous to human CTNNA1 (catenin alpha 1).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ctnna1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
patterned macular dystrophy 2 Alliance Macular dystrophy, patterned, 2 608970
Associated With ctnna1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000633 Vinculin, conserved site
Family IPR001033 Alpha-catenin
Family IPR006077 Vinculin/alpha-catenin
Family IPR030047 Alpha E-catenin/Alpha T-catenin
Homologous_superfamily IPR036723 Alpha-catenin/vinculin-like superfamily
Domain Details Per Protein
Protein Length Alpha-catenin Alpha-catenin/vinculin-like superfamily Alpha E-catenin/Alpha T-catenin Vinculin/alpha-catenin Vinculin, conserved site
UniProtKB:A9JRW0 907
UniProtKB:Q9PVF8 907
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations