Gene

ppm1ab

ID
ZDB-GENE-991102-14
Name
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
Symbol
ppm1ab Nomenclature History
Previous Names
  • pp2ca1
  • wu:fd42g12
  • zgc:153820
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have magnesium ion binding activity; manganese ion binding activity; and protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of canonical Wnt signaling pathway. Predicted to localize to cytosol and nucleus. Orthologous to human PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppm1ab Human Ortholog
No data available
Associated With ppm1ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000222 PPM-type phosphatase, divalent cation binding
Domain IPR001932 PPM-type phosphatase domain
Domain IPR012911 Protein serine/threonine phosphatase 2C, C-terminal
Homologous_superfamily IPR036457 PPM-type phosphatase domain superfamily
Domain Details Per Protein
Protein Length PPM-type phosphatase, divalent cation binding PPM-type phosphatase domain PPM-type phosphatase domain superfamily Protein serine/threonine phosphatase 2C, C-terminal
UniProtKB:Q5TZI2 372
UniProtKB:Q32PM8 338
UniProtKB:Q9PUL5 180
UniProtKB:A0JMI7 333
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations