ZFIN ID: ZDB-GENE-990715-14
Gene Name: myotubularin related protein 2
Gene Symbol: mtmr2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:153915

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity; phosphatidylinositol-3-phosphatase activity; and protein tyrosine phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to localize to cytosol and membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B1. Orthologous to human MTMR2 (myotubularin related protein 2).
Genome Resources: Alliance (1),  Gene:30644 (1),  Ensembl(GRCz11):ENSDARG00000004616 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7329 Point Mutation Unknown Premature Stop ENU
sa26458 Point Mutation Unknown Premature Stop ENU
sa26459 Point Mutation Unknown Splice Site ENU
sa38466 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38467 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mtmr2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Charcot-Marie-Tooth disease type 4B1 Alliance Charcot-Marie-Tooth disease, type 4B1 601382
    DISEASE ASSOCIATED WITH mtmr2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphatidylinositol dephosphorylation (more)
    Cellular Component cytosol (more)
    Molecular Function phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mtmr2-201 (1)    Ensembl 2132
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mtmr2 No data available
    MARKER RELATIONSHIPS
    mtmr2 Contained in: [BAC] DKEY-110K5 (1) (order this)
    mtmr2 Encodes: [cDNA] MGC:153915 (1), MGC:192557 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131371 (1) 2574 nt
    Genomic GenBank:AL929305 (1) 166110 nt
    Select Tool
    Polypeptide UniProtKB:A0JMK5 (1) 620 aa
    Sequence Information (all 18)
    ORTHOLOGY for mtmr2 ( Chr: 5 )
    CITATIONS (25)