Gene
nog3
- ID
- ZDB-GENE-990714-8
- Name
- noggin 3
- Symbol
- nog3 Nomenclature History
- Previous Names
-
- zNog3
- noggin
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Involved in several processes, including embryonic viscerocranium morphogenesis; negative regulation of BMP signaling pathway; and urogenital system development. Predicted to localize to extracellular space. Is expressed in cartilage element; fin; head; and otic vesicle. Human ortholog(s) of this gene implicated in Huntington's disease; cleft lip; dysostosis (multiple); hyperopia; and proximal symphalangism. Orthologous to human NOG (noggin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu301 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ning et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Cystine-knot cytokine | Noggin |
---|---|---|---|
UniProtKB:Q9YHV3
|
223 |
Interactions and Pathways
No data available
Plasmids
No data available