ZFIN ID: ZDB-GENE-990712-18
Gene Name: EYA transcriptional coactivator and phosphatase 1
Gene Symbol: eya1
Sequence Ontology ID : SO:0000704

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Previous Names: dog eared (1), dog (1), wu:fc13c10, zgc:100770

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 65 figures from 42 publications
Directly Submitted Expression Data: 10 figures (24 images) from Rauch et al., 2003 [fc13c10]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
  adenohypophyseal placode, adenohypophysis, anterior lateral line neuromast, anterior lateral line placode (all 33) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
eya1_unspecified Unspecified Unknown Unknown
hi2933Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la014503Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la014504Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022847Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028596Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa3273 Point Mutation Unknown Splice Site ENU
    sa10957 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11723 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • t22744 Point Mutation Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • tc257e Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm90b Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • to15b Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp85b Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-eya1 (1), MO2-eya1 (1)
    PHENOTYPE
    Data: 17 figures from 7 publications
    Observed in: adenohypophysis secretory granule, adenohypophysis, adenohypophysis development, adrenocorticotropic hormone secreting cell (all 44) expand
    DISEASE ASSOCIATED WITH eya1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    branchiootic syndrome Branchiootic syndrome 1 602588
    branchiootorenal syndrome Anterior segment anomalies with or without cataract 113650
    Branchiootorenal syndrome 1, with or without cataracts 113650
    ?Otofaciocervical syndrome 166780
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process adenohypophysis development (more)
    Cellular Component nucleus (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006545 (1)
  • InterPro:IPR028471 (1)
  • InterPro:IPR028472 (1)
  • EC:3.1.3.48 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA eya1-001 (1) 4447
    eya1-002 (1) 2229
    ncRNA eya1-003 (1) 778
    mRNA eya1-004 (1) 723
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM eya1 No data available
    MARKER RELATIONSHIPS
    eya1Contained in: [BAC] DKEY-19O24 (1) (order this), DKEY-94E15 (1) (order this), DKEY-110O13 (1) (order this)
    eya1Encodes: [EST] fc13c10 (1) (order this)
    [cDNA] MGC:100770 (1) (order this), MGC:173810 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131193 (1) 4438bp
    Genomic GenBank:BX510326 (1) 239398bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QNU4 (1) 609aa
    Sequence Clusters UniGene:74747 (1)
    Sequence Information (all 38)
    OTHER eya1 GENE PAGES
  • Alliance (1)
  • Gene:30436 (1)
  • VEGA:OTTDARG00000021374 (1)
  • Ensembl(GRCz10):ENSDARG00000014259 (1)
  • ORTHOLOGY for eya1 (Chr: 24)
    CITATIONS (99)