Gene
wif1
- ID
- ZDB-GENE-990712-17
- Name
- wnt inhibitory factor 1
- Symbol
- wif1 Nomenclature History
- Previous Names
-
- zgc:110507 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have signaling receptor binding activity. Involved in negative regulation of canonical Wnt signaling pathway and swim bladder development. Predicted to localize to cell surface and extracellular region. Is expressed in several structures, including anterior swim bladder bud; nervous system; paraxial mesoderm; pharyngeal arch; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in breast cancer; renal cell carcinoma; and urinary bladder cancer. Orthologous to human WIF1 (WNT inhibitory factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu316 (19 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Yin et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EGF-like, conserved site | EGF-like domain | EGF-like domain, extracellular | WIF domain | WIF domain superfamily | Wnt inhibitory factor (WIF)-1 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9W6F9
|
378 | ||||||
|
UniProtKB:Q5TZI0
|
378 |
Interactions and Pathways
No data available
Plasmids
No data available