ZFIN ID: ZDB-GENE-990712-17
Gene Name: wnt inhibitory factor 1
Gene Symbol: wif1
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:110507 (1)

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have signaling receptor binding activity; involved in negative regulation of canonical Wnt signaling pathway and swim bladder development; predicted to localize to the cell surface and  ...
GENE EXPRESSION
All Expression Data: 14 figures from 8 publications
Directly Submitted Expression Data: 6 figures (19 images) from Thisse et al., 2005 [eu316]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028970Tg Transgenic Insertion Unknown Unknown DNA
Targeting reagents:
PHENOTYPE
Data: 4 figures from Yin et al., 2012
Observed in:
DISEASE ASSOCIATED WITH wif1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH wif1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of canonical Wnt signaling pathway (more)
Cellular Component extracellular region (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000742 (1)
  • InterPro:IPR003306 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013111 (1)
  • InterPro:IPR013309 (1)
  • InterPro:IPR038677 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50814 (1)
  • Pfam:PF02019 (1)
  • Pfam:PF07974 (1)
  • Pfam:PF12661 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wif1-001 (1) 1883
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM wif1 No data available
    MARKER RELATIONSHIPS
    wif1Contained in: [BAC] DKEY-6A5 (1) (order this)
    wif1Encodes: [EST] eu316 (1)
    [cDNA] MGC:110507 (1) (order this), MGC:192912 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131229 (1) 1897bp
    Genomic GenBank:BX119963 (1) 229125bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q5TZI0 (1) 378aa
    Sequence Clusters UniGene:3690 (1)
    Sequence Information (all 22)
    OTHER wif1 GENE PAGES
  • Alliance (1)
  • Gene:30476 (1)
  • VEGA:OTTDARG00000007871 (1)
  • Ensembl(GRCz11):ENSDARG00000005541 (2)
  • ORTHOLOGY for wif1 (Chr: 4)
    CITATIONS (40)