Gene

svila

ID
ZDB-GENE-990706-5
Name
supervillin a
Symbol
svila Nomenclature History
Previous Names
  • svil
  • sb:cb867
  • wu:fd05a09
  • zmp:0000000648 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in actin filament severing; actin polymerization or depolymerization; and barbed-end actin filament capping. Predicted to localize to actin cytoskeleton and cytoplasm. Is expressed in several structures, including adaxial cell; cardiovascular system; musculature system; optic vesicle; and sensory system. Orthologous to human SVIL (supervillin).
Genome Resources
Note
None
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Deo et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With svila Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
myofibrillar myopathy 10 Alliance Myofibrillar myopathy 10 619040
Associated With svila Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003128 Villin headpiece
Domain IPR007123 Gelsolin-like domain
Family IPR007122 Villin/Gelsolin
Family IPR015628 Supervillin
Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
Homologous_superfamily IPR036886 Villin headpiece domain superfamily
Domain Details Per Protein
Protein Length ADF-H/Gelsolin-like domain superfamily Gelsolin-like domain Supervillin Villin/Gelsolin Villin headpiece Villin headpiece domain superfamily
UniProtKB:U3JAA5 111
UniProtKB:U3JA36 184
UniProtKB:Q7SX87 553
UniProtKB:A9JRM6 1642
UniProtKB:A0A2R8Q3W8 1761
UniProtKB:A0A2R8Q0D6 1756
UniProtKB:U3JAV9 170
UniProtKB:A9JRQ4 695
UniProtKB:U3JAT5 136
UniProtKB:Q38HW9 1763
UniProtKB:F1Q6K8 1763
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations