ZFIN ID: ZDB-GENE-990706-5
Gene Name: supervillin a
Gene Symbol: svila    Nomenclature History

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Previous Names: svil, sb:cb867, wu:fd05a09, zmp:0000000648 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Predicted to be involved in cytoskeleton organization. Is expressed in several structures, including adaxial cell; cardiovascular system; musculature system; optic vesicle; and sensory system. Orthologous to human SVIL (supervillin).
Genome Resources: Alliance (1),  Gene:30112 (1),  Ensembl(GRCz11):ENSDARG00000055075 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010120Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la012156Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11202 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12766 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14626 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14627 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14853 Point Mutation Unknown Premature Stop ENU
    sa17102 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17252 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38892 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-svila N/A 2
    PHENOTYPE
    Data: Fig. 5 from Deo et al., 2014
    Observed in:
    DISEASE ASSOCIATED WITH svila HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH svila VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cytoskeleton organization (more)
    Molecular Function actin binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR003128 Villin headpiece
    Family IPR007122 Villin/Gelsolin
    Domain IPR007123 Gelsolin-like domain
    Family IPR015628 Supervillin
    Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
    Homologous_superfamily IPR036886 Villin headpiece domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript svila-207 (1)    Ensembl 750
    mRNA svila-201 (1)    Ensembl 6407
    svila-202 (1)    Ensembl 511
    svila-203 (1)    Ensembl 2851
    svila-204 (1)    Ensembl 553
    svila-205 (1)    Ensembl 896
    ncRNA svila-005 (1)    Ensembl 378
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM svila No data available
    MARKER RELATIONSHIPS
    svila Contained in: [BAC] CH211-191J18 (1), CH211-203C7 (1)
    svila Encodes: [EST] cb867 (1), fd05a09, IMAGE:2600647
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001035261 (1) 6426 bp
    Genomic GenBank:BX005400 (1) 152580 bp
    Select Tool
    Polypeptide UniProtKB:F1Q6K8 (1) 1763 aa
    Sequence Information (all 44)
    ORTHOLOGY for svila ( Chr: 12 )
    CITATIONS (27)