Gene

lmnb2

ID
ZDB-GENE-990630-13
Name
lamin B2
Symbol
lmnb2 Nomenclature History
Previous Names
  • fc15d06
  • im:7142331
  • lamin (1)
  • wu:fb94e05
  • wu:fb95e12
  • wu:fc15d06
  • wu:fc49h03
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Localizes to nuclear envelope. Human ortholog(s) of this gene implicated in partial lipodystrophy and progressive myoclonus epilepsy 9. Orthologous to human LMNB2 (lamin B2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lmnb2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
progressive myoclonus epilepsy 9 Alliance ?Epilepsy, progressive myoclonic, 9 616540
{Lipodystrophy, partial, acquired, susceptibility to} 608709
Associated With lmnb2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR001322 Lamin tail domain
Domain IPR039008 Intermediate filament, rod domain
Homologous_superfamily IPR036415 Lamin tail domain superfamily
Homologous_superfamily IPR042180 Intermediate filament, rod domain, coil 1B
Domain Details Per Protein
Protein Length Intermediate filament protein, conserved site Intermediate filament, rod domain Intermediate filament, rod domain, coil 1B Lamin tail domain Lamin tail domain superfamily
UniProtKB:Q9W6T5 583
UniProtKB:B3DFN3 583
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations