ZFIN ID: ZDB-GENE-990621-3
Gene Name: dopamine beta-hydroxylase (dopamine beta-monooxygenase)
Gene Symbol: dbh
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 40 figures from 26 publications
Wild-type Stages, Structures: Segmentation:26+ somites (22.0h-24.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ct806 Insertion Exon 3 Premature Stop ZINC_FINGER_NUCLEASE
sa21676 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24865 Point Mutation Unknown Splice Site ENU
    PHENOTYPE
    Data: 2 figures from Singh et al., 2015
    Observed in:
    DISEASE ASSOCIATED WITH dbh HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    dopamine beta-hydroxylase deficiency Orthostatic hypotension 1, due to DBH deficiency 223360
    DISEASE ASSOCIATED WITH dbh VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process sleep (more)
    Cellular Component integral component of membrane (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000323 (1)
  • InterPro:IPR005018 (1)
  • InterPro:IPR008977 (1)
  • InterPro:IPR014783 (1)
  • InterPro:IPR014784 (1)
  • InterPro:IPR024548 (1)
  • InterPro:IPR028460 (1)
  • InterPro:IPR036939 (1)
  • PROSITE:PS00085 (1)
  • PROSITE:PS50836 (1)
  • Pfam:PF01082 (1)
  • Pfam:PF03351 (1)
  • Pfam:PF03712 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dbh-001 (1) 1953
    ncRNA dbh-002 (1) 858
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM dbh
    MARKER RELATIONSHIPS
    dbhContained in: [BAC] CH211-270H11 (1) (order this)
    dbhEncodes: [cDNA] MGC:194632 (1) (order this), MGC:194650 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001109694 (1) 1845bp
    Genomic GenBank:AL935290 (1) 129665bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8QLP9 (1) 614aa
    Sequence Clusters UniGene:21021 (1)
    Sequence Information (all 17)
    OTHER dbh GENE PAGES
  • Alliance (1)
  • Gene:30505 (1)
  • VEGA:OTTDARG00000019526 (1)
  • ORTHOLOGY for dbh (Chr: 10)
    CITATIONS (63)