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ZIRC
ZFIN ID: ZDB-GENE-990603-8
Gene Name: SMAD family member 4a
Gene Symbol: smad4a
Sequence Ontology ID : SO:0000704

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Previous Names: madh4, smad4, SMA- and MAD-related protein 4, zmp:0000000768

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits protein heterodimerization activity and sequence-specific DNA binding activity. Contributes to transcription regulatory region DNA binding activity. Involved in several processes, including  ...
GENE EXPRESSION
All Expression Data: 6 figures from 5 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10804 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH smad4a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    juvenile polyposis syndrome Polyposis, juvenile intestinal 174900
    pancreatic carcinoma Pancreatic cancer, somatic 260350
    Myhre syndrome 139210
    Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome 175050
    DISEASE ASSOCIATED WITH smad4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process convergent extension (more)
    Cellular Component nucleus (more)
    Molecular Function protein heterodimerization activity (more)
    GO Terms (all 16)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM smad4a No data available
    MARKER RELATIONSHIPS
    smad4aEncodes: [cDNA] MGC:194729 (1), MGC:194736 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001122700 (1) 2744bp
    Genomic GenBank:CU929306 (1) 35764bp
    Select Tool
    Polypeptide UniProtKB:B1PS58 (1) 547aa
    Sequence Clusters UniGene:8327 (1)
    Sequence Information (all 31)
    OTHER smad4a GENE PAGES
  • Alliance (1)
  • Gene:559111 (1)
  • Ensembl(GRCz11):ENSDARG00000075226 (2)
  • ORTHOLOGY for smad4a (Chr: 10)
    CITATIONS (35)