Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-90
Gene Name: hairy-related 5
Gene Symbol: her5
Previous Name: zgc:136537
Nomenclature History
GENE EXPRESSION
All Expression Data: 39 figures from 28 publications
Directly Submitted Expression Data: 6 figures (15 images) from Thisse et al., 2005 [eu359]
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Hatching:Long-pec (48.0h-60.0h)
  endodermal cell, hindbrain neural keel anterior region, hypoblast, margin (all 16) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa12026
Knockdown reagents: MO1-her5 (1), MO2-her5 (1)
PHENOTYPE
Data: Fig. 6 from Shin et al., 2008
Observed in: endodermal cell fate specification, hepatic duct, liver, liver development (all 7) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Spondylocostal dysostosis 4, autosomal recessive 613686
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic organ morphogenesis (more)
Cellular Component nucleus (more)
Molecular Function protein binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003650 (1)
  • InterPro:IPR011598 (1)
  • PROSITE:PS50888 (1)
  • PROSITE:PS51054 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA her5-001 (1) 1344
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM her5
    Tg(-0.7her5:EGFP), Tg(-1.7her5:EGFP), Tg(-3.4her5:EGFP), Tg(her5:mCherry-CAAX)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    her5 Contained in: [BAC] CH73-271E23 (1) (order this), CH211-153K16 (1) (order this)
    her5 Encodes: [EST] eu359 (1)
    [cDNA] MGC:136537 (1) (order this), MGC:158599 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131077 (1) 1179 bp
    Genomic GenBank:BX323810 166625 bp
    Select Tool
    Polypeptide UniProtKB:F1QJS9 (1) 227 aa
    Sequence Clusters UniGene:75071 (1)
    Sequence Information (all 21)
    OTHER her5 GENE PAGES
  • Gene:30285 (1)
  • VEGA:OTTDARG00000031796 (1)
  • Ensembl(Zv9):ENSDARG00000008796 (1)
  • MAPPING INFORMATION
    Chr: 14 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish her5 14  
    Human HES7 17 (17p13.1)
  • OMIM:608059
  • Gene:84667
  • CITATIONS (74)