ZFIN ID: ZDB-GENE-990415-90
Gene Name: hairy-related 5
Gene Symbol: her5

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Previous Name: zgc:136537

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Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 41 figures from 30 publications
Directly Submitted Expression Data: 6 figures (15 images) from Thisse et al., 2005 [eu359]
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Hatching:Long-pec (48.0h-60.0h)
  endoderm, endodermal cell, EVL, hindbrain neural keel anterior region (all 18) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12026 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-her5 (1), MO2-her5 (1)
    PHENOTYPE
    Data: Fig. 6 from Shin et al., 2008
    Observed in: endodermal cell fate specification, hepatic duct, liver, liver development (all 7) expand
    DISEASE ASSOCIATED WITH her5 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    spondylocostal dysostosis Spondylocostal dysostosis 4, autosomal recessive 613686
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic organ morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function protein binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003650 (1)
  • InterPro:IPR011598 (1)
  • InterPro:IPR032644 (1)
  • PROSITE:PS50888 (1)
  • PROSITE:PS51054 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA her5-001 (1) 1326
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM her5
    Tg(-0.7her5:EGFP), Tg(-1.7her5:EGFP), Tg(-3.4her5:EGFP), Tg(her5:mCherry-CAAX)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    her5Contained in: [BAC] CH73-271E23 (1) (order this), CH211-153K16 (1) (order this)
    her5Encodes: [EST] eu359 (1)
    [cDNA] MGC:136537 (1) (order this), MGC:158599 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131077 (1) 1179bp
    Genomic GenBank:BX323810 166625bp
    Select Tool
    Polypeptide UniProtKB:Q504H7 (1) 225aa
    Sequence Clusters UniGene:75071 (1)
    Sequence Information (all 21)
    OTHER her5 GENE PAGES
  • Gene:30285 (1)
  • VEGA:OTTDARG00000031796 (1)
  • Ensembl(GRCz10):ENSDARG00000008796 (1)
  • ORTHOLOGY for her5 (Chr: 14)
    Species Symbol Chromosome Accession # Evidence
    Human HES7 17
  • Gene:84667
  • OMIM:608059
  • HGNC:15977
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (82)