ZFIN ID: ZDB-GENE-990415-75
Gene Name: notochord homeobox
Gene Symbol: noto
Sequence Ontology ID : SO:0000704

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Previous Names: Znot, flh, floating head

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 101 figures from 82 publications
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  anterior neural keel, axial chorda mesoderm, axial hypoblast, axial mesoderm (all 36) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la620 Unknown Unknown Unknown ENU
la018405Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m614 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • n1 Small Deletion Unknown Unknown SPONTANEOUS
  • Zebrafish International Resource Center (ZIRC) (order this)
  • noto_unspecified Unspecified Unknown Unknown
    sa42164 Point Mutation Unknown Premature Stop ENU
    tk241 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm229 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-noto (1), MO2-noto (1), MO3-noto (1)
    PHENOTYPE
    Data: 50 figures from 29 publications
    Observed in: adaxial cell, angioblast cell migration from lateral mesoderm to midline, axial chorda mesoderm cell fate commitment, axial chorda mesoderm (all 70) expand
    DISEASE ASSOCIATED WITH noto HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axial mesoderm morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 26)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA noto-001 (1) 991
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM noto
    Tg(-1.6flh:GAP-EGFP), Tg(flh:EGFP), TgBAC(flh:flh-Kaede)
    MARKER RELATIONSHIPS
    notoContained in: [BAC] DKEY-159C24 (1) (order this)
    notoEncodes: [cDNA] MGC:193971 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131055 (1) 953bp
    Genomic GenBank:BX571943 (1) 193538bp
    Select Tool
    Polypeptide UniProtKB:B8A5N9 (1) 241aa
    Sequence Clusters UniGene:352 (1)
    Sequence Information (all 14)
    OTHER noto GENE PAGES
  • Alliance (1)
  • Gene:30260 (1)
  • VEGA:OTTDARG00000020758 (1)
  • Ensembl(GRCz10):ENSDARG00000021201 (1)
  • ORTHOLOGY for noto (Chr: 13)
    CITATIONS (253)