ZFIN ID: ZDB-GENE-990415-73
Gene Name: fibulin 1
Gene Symbol: fbln1    Nomenclature History

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Previous Names: fbln1c (1), fbln1d (1), wu:fc52c06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity and peptidase activator activity. Involved in several processes, including embryonic medial fin morphogenesis; mesenchymal cell migration; and skin morphogenesis. Predicted to localize to extracellular region. Is expressed in atrioventricular canal; mesenchyme median fin fold; mesoderm; somite; and tail bud. Orthologous to human FBLN1 (fibulin 1).
Genome Resources: Alliance (1),  Gene:30240 (1),  Ensembl(GRCz11):ENSDARG00000103311 (1)
GENE EXPRESSION
All Expression Data: 8 figures from 5 publications
Directly Submitted Expression Data: 4 figures (11 images) from Rauch et al., 2003 [fc52c06]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-fbln1 N/A 1
MO2-fbln1 N/A 1
MO3-fbln1 N/A 1
MO4-fbln1 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH fbln1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
synpolydactyly Alliance Synpolydactyly, 3/3'4, associated with metacarpal and metatarsal synostoses 608180
DISEASE ASSOCIATED WITH fbln1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic medial fin morphogenesis (more)
Cellular Component extracellular region (more)
Molecular Function calcium ion binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fbln1 No data available
MARKER RELATIONSHIPS
fbln1 Encodes: [EST] fc52c06 (order this)
[cDNA] MGC:193899 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131042 (1) 2415 nt
Genomic GenBank:CU694219 (1) 31777 nt
Select Tool
Polypeptide UniProtKB:B3DH18 (1) 681 aa
Sequence Information (all 26)
ORTHOLOGY for fbln1 ( Chr: 25 )
CITATIONS (28)