Gene

ephb3a

ID
ZDB-GENE-990415-60
Name
eph receptor B3a
Symbol
ephb3a Nomenclature History
Previous Names
  • ek3
  • epha3a
  • rtk3 (1)
  • zek3
  • fc62d03
  • wu:fc62d03
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have transmembrane-ephrin receptor activity. Predicted to be involved in several processes, including neuron projection development; positive regulation of synapse assembly; and substrate adhesion-dependent cell spreading. Predicted to localize to integral component of plasma membrane; neuron projection; and receptor complex. Is expressed in several structures, including anterior neural keel; central nervous system; hypoblast; immature eye; and mesoderm. Orthologous to human EPHB3 (EPH receptor B3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ephb3a Human Ortholog
No data available
Associated With ephb3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008266 Tyrosine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Conserved_site IPR001426 Tyrosine-protein kinase, receptor class V, conserved site
Domain IPR000719 Protein kinase domain
Domain IPR001090 Ephrin receptor ligand binding domain
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain IPR001660 Sterile alpha motif domain
Domain IPR003961 Fibronectin type III
Domain IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like
Domain IPR020635 Tyrosine-protein kinase, catalytic domain
Domain IPR027936 Ephrin receptor, transmembrane domain
Domain IPR034245 Ephrin type-B receptor 3, ligand binding domain
Family IPR016257 Ephrin receptor type-A /type-B
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Domain Details Per Protein
Protein Length Ephrin receptor ligand binding domain Ephrin receptor, transmembrane domain Ephrin receptor type-A /type-B Ephrin type-B receptor 3, ligand binding domain Fibronectin type III Fibronectin type III superfamily Galactose-binding-like domain superfamily Growth factor receptor cysteine-rich domain superfamily Immunoglobulin-like fold Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine-threonine/tyrosine-protein kinase, catalytic domain Sterile alpha motif domain Tyrosine-protein kinase, active site Tyrosine-protein kinase, catalytic domain Tyrosine-protein kinase ephrin type A/B receptor-like Tyrosine-protein kinase, receptor class V, conserved site
UniProtKB:B8JKB8 925
UniProtKB:Q90ZN8 923
UniProtKB:O13147 500
UniProtKB:A0A0B5JSD1 535
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations